Mitochondrial carriers function as monomers

Exosomes as miRNA Carriers: Formation–Function–Future

Exosomes, which are one of the smallest extracellular vesicles released from cells, have been shown to carry different nucleic acids, including microRNAs (miRNAs). miRNAs significantly regulate cell growth and metabolism by posttranscriptional inhibition of gene expression. The rapidly changing understanding of exosomes' formation and function in delivering miRNAs from cell to cell has prompted...

Anion Carriers of Mitochondrial Membranes

Role of Mitochondrial Carriers in Metabolic Engineering

Gennaro Agrimi1,2*, Annamaria Russo1,2 and Maria Antonietta Ricci1,2 1Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Via Orabona 4, 70125 Bari, Italy 2CIRCC Interuniversity Consortium Chemical Reactivity and Catalysis, Via Celso Ulpiani 27, 70126 Bari, Italy *Corresponding author: Gennaro Agrimi, Assistant professor, Department of Biosciences, Biotechnologi...

Evolution, structure and function of mitochondrial carriers: a review with new insights.

The mitochondrial carriers (MC) constitute a large family (MCF) of inner membrane transporters displaying different substrate specificities, patterns of gene expression and even non-mitochondrial organelle localization. In Arabidopsis thaliana 58 genes encode these six trans-membrane domain proteins. The number in other sequenced plant genomes varies from 37 to 125, thus being larger than that ...

Acyl hydrazides as peptoid sub-monomers.

The use of acyl hydrazides as peptoid sub-monomers is investigated. We demonstrate here that azapeptoids derived entirely from acyl hydrazides can be made conveniently and efficiently using standard peptoid sub-monomer chemistry. Structural studies reveal that the main chain amide bond in these molecules predominantly adopts a trans conformation. A high-quality one bead one compound library of ...